Myeloproliferative Neoplasms
What are Myeloproliferative neoplasms (MPN)
- MPN stands for myeloproliferative neoplasms
- MPN belong to a group of rare diseases of the bone marrow
- MPN are blood cancers, occurring when the body produces to many red and/or white blood cells and/or platelets
Under the umbrella of myeloproliferative neoplasms (MPNs) there are different diseases that belong to the family of malignancies. MPNs are completely different from solid cancers since MPNs are chronic diseases mostly. MPNs develop in the bone marrow of the patients which produce too many blood cells. According to the category of blood cells that are predominant, we can classify these diseases into different categories
MPN Classification of the World Health Organization (WHO)
The classification of myeloid neoplasms by the WHO, revised in 2016, encompasses the following myeloproliferative neoplasms (MPN):
- Chronic myeloid leukaemia (CML)
- BCR-ABL1+ chronic neutrophilic leukaemia (CNL)
- Polycythaemia vera (PV)
- Primary myelofibrosis (PMF)
- Essential thrombocythaemia (ET)
- Chronic eosinophilic leukaemia, not otherwise specified (NOS)
- Myeloproliferative neoplasms, unclassified (MPN, U)
Source: The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
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